Download BookMouse Models for Drug Discovery Methods and Protocols

[Free Ebook.nvVO] Mouse Models for Drug Discovery Methods and Protocols

[Free Ebook.nvVO] Mouse Models for Drug Discovery Methods and Protocols

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Book Details :
Published on: 2010-04-29
Released on:
Original language: English

As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal model studies. In Mouse Models for Drug Discovery: Methods and Protocols, experts in the field present some background for those less familiar with mice as experimental model platforms as well as a collection of techniques involving general methods as well as specific disease topics such as type 1 and 2 diabetes, cardiovascular disease, arthritis, skin disorders, cancer, the use of behavioral models for depression and anxiety, neurodegenerative diseases, neuromuscular diseases, and infectious diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy-to-use, Mouse Models for Drug Discovery: Methods and Protocols will stimulate those not familiar with the power of the mouse and its potential for the drug discovery process, and it will encourage the development of new models and new ways to utilize existing models in order to further the use of this dynamic animal in this vital field. Methods in Enzymology - ScienceDirect.com Methods in Enzymology Volume 586 Pages 2-515 (2017) Proteomics in Biology Part B B A B Y L O N F L O R A L A Unique Denver Florist Welcome to Babylon Floral Design Denver's most unique flower boutique specializing in cutting edge floral design and unique gift items. We strive to provide the ... The Truth About Hydrazine Sulfate - Dr. Gold Speaks For some time now I have refrained from making any comments in regard to information on the Internet concerning hydrazine sulfate. My silence has been occasioned by ... Analytical Instrument Repair & Calibration Moyer Instruments Inc. offers repair or calibration of analytical laboratory instruments such as Spectrophotometers GC AA TGA TOC HPLC pH meters Analyzers ... PicoTrace .de PicoTrace is a spin-off company founded by members of the Faculty of Geosciences of the University of Gttingen Germany. Our University has a well known tradition ... Processes for Constructing Homogeneous Antibody Drug ... Antibody drug conjugates (ADCs) are a rapidly growing class of targeted therapeutic agents for treatment of cancer. Although the number of ADCs in clinical trials has ... Maximizing mouse cancer models : Article : Nature Reviews ... Animal models of cancer provide an alternative means to determine the causes of and treatments for malignancy thus representing a resource of immense potential for ... Islet Transplantation in Seven Patients with Type 1 ... Methods. Seven consecutive patients with type 1 diabetes and a history of severe hypoglycemia and metabolic instability underwent islet transplantation in conjunction ... Home - Springer Providing researchers with access to millions of scientific documents from journals books series protocols and reference works. Current advances in humanized mouse models - Nature Top of page Introduction Humanized mouse models in which various types of human cells and tissues are engrafted and function as they would in humans are ...
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